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Multiphysics Modeling with Application to Biomedical Engineering

Author : Z. Yang
Publisher : Unknown
Release : 2020
Category : Uncategorized
ISBN : 0367509768

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Book Multiphysics Modeling with Application to Biomedical Engineering Description/Summary:

"The aim of this book is to introduce the simulation of various physical fields and their applications for biomedical engineering, which will provide a base for researchers in the biomedical field to conduct further investigation. The entire book is classified into three levels. It starts with the first level, which presents the single physical fields including structural analysis, fluid simulation, thermal analysis, and acoustic modeling. Then, the second level consists of various couplings between two physical fields covering structural thermal coupling, porous media, fluid structural interaction (FSI), and acoustic FSI. The third level focuses on multi-coupling that coupling with more than two physical fields in the model. Each part in all levels is organized as the physical feature, finite element implementation, modeling procedure in ANSYS, and the specific applications for biomedical engineering like the FSI study of Abdominal Aortic Aneurysm (AAA), acoustic wave transmission in the ear, and heat generation of the breast tumor. The book should help for the researchers and graduate students conduct numerical simulation of various biomedical coupling problems. It should also provide all readers with a better understanding of various couplings"--

Multiphysics Modeling with Application to Biomedical Engineering

Author : Z. Yang
Publisher : CRC Press
Release : 2020-07-23
Category : Mathematics
ISBN : 9781000088878

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Book Multiphysics Modeling with Application to Biomedical Engineering Description/Summary:

The aim of this book is to introduce the simulation of various physical fields and their applications for biomedical engineering, which will provide a base for researchers in the biomedical field to conduct further investigation. The entire book is classified into three levels. It starts with the first level, which presents the single physical fields including structural analysis, fluid simulation, thermal analysis, and acoustic modeling. Then, the second level consists of various couplings between two physical fields covering structural thermal coupling, porous media, fluid structural interaction (FSI), and acoustic FSI. The third level focuses on multi-coupling that coupling with more than two physical fields in the model. Each part in all levels is organized as the physical feature, finite element implementation, modeling procedure in ANSYS, and the specific applications for biomedical engineering like the FSI study of Abdominal Aortic Aneurysm (AAA), acoustic wave transmission in the ear, and heat generation of the breast tumor. The book should help for the researchers and graduate students conduct numerical simulation of various biomedical coupling problems. It should also provide all readers with a better understanding of various couplings.

Multiphysics Modeling: Numerical Methods and Engineering Applications

Author : Qun Zhang,Song Cen
Publisher : Elsevier
Release : 2015-12-15
Category : Technology & Engineering
ISBN : 9780124077379

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Book Multiphysics Modeling: Numerical Methods and Engineering Applications Description/Summary:

Multiphysics Modeling: Numerical Methods and Engineering Applications: Tsinghua University Press Computational Mechanics Series describes the basic principles and methods for multiphysics modeling, covering related areas of physics such as structure mechanics, fluid dynamics, heat transfer, electromagnetic field, and noise. The book provides the latest information on basic numerical methods, also considering coupled problems spanning fluid-solid interaction, thermal-stress coupling, fluid-solid-thermal coupling, electromagnetic solid thermal fluid coupling, and structure-noise coupling. Users will find a comprehensive book that covers background theory, algorithms, key technologies, and applications for each coupling method. Presents a wealth of multiphysics modeling methods, issues, and worked examples in a single volume Provides a go-to resource for coupling and multiphysics problems Covers the multiphysics details not touched upon in broader numerical methods references, including load transfer between physics, element level strong coupling, and interface strong coupling, amongst others Discusses practical applications throughout and tackles real-life multiphysics problems across areas such as automotive, aerospace, and biomedical engineering

Computational Modeling in Biomedical Engineering and Medical Physics

Author : Alexandru Morega,Mihaela Morega,Alin Dobre
Publisher : Academic Press
Release : 2020-09-15
Category : Science
ISBN : 9780128178980

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Book Computational Modeling in Biomedical Engineering and Medical Physics Description/Summary:

Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies. Presents the fundamentals of mathematical and numerical modeling of engineering problems in medicine Discusses many of the most common modelling scenarios for Biomedical Engineering, including, electrical activity of the heart hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods Includes discussion of the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling, physics scaling, Constructal Law criteria in morphing shape and structure of systems with internal flows, computational domain construction, numerical modelling issues, and validation techniques used to ascertain numerical simulation results

Modelling Organs, Tissues, Cells and Devices

Author : Socrates Dokos
Publisher : Springer
Release : 2017-03-08
Category : Technology & Engineering
ISBN : 9783642548017

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Book Modelling Organs, Tissues, Cells and Devices Description/Summary:

This book presents a theoretical and practical overview of computational modeling in bioengineering, focusing on a range of applications including electrical stimulation of neural and cardiac tissue, implantable drug delivery, cancer therapy, biomechanics, cardiovascular dynamics, as well as fluid-structure interaction for modelling of organs, tissues, cells and devices. It covers the basic principles of modeling and simulation with ordinary and partial differential equations using MATLAB and COMSOL Multiphysics numerical software. The target audience primarily comprises postgraduate students and researchers, but the book may also be beneficial for practitioners in the medical device industry.

Computational Bioengineering

Author : Guigen Zhang
Publisher : CRC Press
Release : 2015-04-01
Category : Medical
ISBN : 9781466517561

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Book Computational Bioengineering Description/Summary:

Arguably the first book of its kind, Computational Bioengineering explores the power of multidisciplinary computer modeling in bioengineering. Written by experts, the book examines the interplay of multiple governing principles underlying common biomedical devices and problems, bolstered by case studies. It shows you how to take advantage of the la

An Introduction to Modeling of Transport Processes

Author : Ashim Datta,Vineet Rakesh
Publisher : Cambridge University Press
Release : 2010
Category : Science
ISBN : 9780521119245

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Book An Introduction to Modeling of Transport Processes Description/Summary:

Organised around problem solving, this book introduces the reader to computational simulation, bridging fundamental theory with real-world applications.

Introduction to Integrative Engineering

Author : Guigen Zhang
Publisher : CRC Press
Release : 2017-03-03
Category : Health & Fitness
ISBN : 9781315388458

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Book Introduction to Integrative Engineering Description/Summary:

This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based computational modeling methods, provides detailed step-by-step techniques to build a model with consideration of underlying multiphysics, and discusses many important aspects of a modeling approach including results interpretation, validation, and assessment.

Multiphysics Modeling Using COMSOL 5 and MATLAB

Author : Roger W. Pryor, PhD
Publisher : Mercury Learning and Information
Release : 2021-12-03
Category : Technology & Engineering
ISBN : 9781683925880

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Book Multiphysics Modeling Using COMSOL 5 and MATLAB Description/Summary:

COMSOL 5 and MATLAB are valuable software modeling tools for engineers and scientists. This updated edition includes five new models and explores a wide range of models in coordinate systems from 0D to 3D, introducing the numerical analysis techniques employed in COMSOL 5.6 and MATLAB software. The text presents electromagnetic, electronic, optical, thermal physics, and biomedical models as examples. It presents the fundamental concepts in the models and the step-by-step instructions needed to build each model. The companion files include all the built models for each step-by-step example presented in the text and the related animations, as specified. The book is designed to introduce modeling to an experienced engineer or can also be used for upper level undergraduate or graduate courses. FEATURES: Focuses on COMSOL 5.x and MATLAB models that demonstrate the use of concepts for later application in engineering, science, medicine, and biophysics for the development of devices and systems Includes companion files with executable copies of each model and related animations Includes detailed discussions of possible modeling errors and results Uses a step-by-step modeling methodology linked to the Fundamental Laws of Physics. The companion files are also available online by emailing the publisher with proof of purchase at [email protected]

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences

Author : Riccardo Sacco,Giovanna Guidoboni,Aurelio Giancarlo Mauri
Publisher : Academic Press
Release : 2019-07-18
Category : Technology & Engineering
ISBN : 9780128125199

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Book A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences Description/Summary:

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives Features examples, exercises, and MATLAB codes for further reader involvement Covers basic and advanced functional and computational techniques throughout the book

Computational Bioengineering and Bioinformatics

Author : Nenad Filipovic
Publisher : Springer Nature
Release : 2020-03-11
Category : Technology & Engineering
ISBN : 9783030436582

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Book Computational Bioengineering and Bioinformatics Description/Summary:

This book explores the latest and most relevant topics in the field of computational bioengineering and bioinformatics, with a particular focus on patient-specific, disease-progression modeling. It covers computational methods for cardiovascular disease prediction, with an emphasis on biomechanics, biomedical decision support systems, data mining, personalized diagnostics, bio-signal processing, protein structure prediction, biomedical image processing, analysis and visualization, and high-performance computing. It also discusses state-of-the-art tools for disease characterization, and recent advances in areas such as biomechanics, cardiovascular engineering, patient-specific modeling, population-based modeling, multiscale modeling, image processing, data mining, biomedical decision-support systems, signal processing, biomaterials and dental biomechanics, tissue and cell engineering, computational chemistry and high-performance computing. As such, it is a valuable resource for researchers, medical and bioengineering students, and medical device and software experts

Multiphysics and Multiscale Modeling

Author : Young W. Kwon
Publisher : CRC Press
Release : 2015-10-05
Category : Science
ISBN : 9781498782524

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Book Multiphysics and Multiscale Modeling Description/Summary:

Written to appeal to a wide field of engineers and scientists who work on multiscale and multiphysics analysis, Multiphysics and Multiscale Modeling: Techniques and Applications is dedicated to the many computational techniques and methods used to develop man-made systems as well as understand living systems that exist in nature. Presenting a body

COMSOL for Engineers

Author : Mehrzad Tabatabaian
Publisher : Mercury Learning and Information
Release : 2014-03-31
Category : Science
ISBN : 9781938549564

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Book COMSOL for Engineers Description/Summary:

COMSOL Multiphysics software is one of the most valuable software modeling tools for engineers and scientists. This book is designed for engineers from the fields of mechanical, electrical, and civil disciplines, and introduces multiphysics modeling techniques and examples accompanied by practical applications using COMSOL 4.x. The book includes a companion CD-ROM with files of over 25 models, images, and code. The main objective is to introduce readers to use COMSOL as an engineering tool for modeling by solving examples that could become a guide for modeling similar or more complicated problems. The objective is to provide a collection of examples and modeling guidelines through which readers can build their own models. Readers are assumed to be familiar with the principles of numerical modeling and the finite element method (FEM). The book takes a flexible-level approach for presenting the materials along with using practical examples. The mathematical fundamentals, engineering principles, and design criteria are presented as integral parts of examples. At the end of each chapter are references that contain more in-depth physics, technical information, and data; these are referred to throughout the book and used in the examples. COMSOL for Engineers could be used to complement another text that provides background training in engineering computations and methods. Examples provided in this book should be considered as "lessons" for which background physics could be explained in more detail. FEATURES Includes a companion CD-ROM with files of over 25 models, images,code Uses progressive approach in terms of examples and models eBook Customers: Companion files are available for downloading with order number/proof of purchase by writing to the publisher at [email protected]

Geometry Creation and Import With COMSOL Multiphysics

Author : Layla S. Mayboudi
Publisher : Mercury Learning and Information
Release : 2019-09-20
Category : Technology & Engineering
ISBN : 9781683922148

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Book Geometry Creation and Import With COMSOL Multiphysics Description/Summary:

This book focuses on the geometry creation techniques for use in finite element analysis. Examples are provided as a sequence of fin designs with progressively increasing complexity. A fin was selected as it is a feature widely employed for thermal management. As the content progresses, the reader learns to create or import a geometry into a FEM tool using COMSOL Multiphysics®. The fundamentals may also be applied to other commercial packages such as ANSYS® or AbaqusTM. The content can be utilized in a variety of engineering disciplines including mechanical, aerospace, biomedical, chemical, civil, and electrical. The book provides an overview of the tools available to create and interact with the geometry. It also takes a broader look on the world of geometry, showing how geometry is a fundamental part of nature and how it is interconnected with the world around us. Features: Includes example models that enable the reader to implement conceptual material in practical scenarios with broad industrial applications Provides geometry modeling examples created with built in features of COMSOL Multiphysics® v. 5.4 or imported from other dedicated CAD tools Presents meshing examples and provides practical advice on mesh generation Includes companion files with models and custom applications created with COMSOL Multiphysics® Application Builder.

Cells—Advances in Research and Application: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
Category : Science
ISBN : 9781464990496

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Book Cells—Advances in Research and Application: 2012 Edition Description/Summary:

Cells—Advances in Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cells. The editors have built Cells—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cells in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cells—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

Author : Willem van Meurs
Publisher : McGraw Hill Professional
Release : 2011-08-07
Category : Technology & Engineering
ISBN : 9780071714464

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Book Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology Description/Summary:

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

Time Delay ODE/PDE Models

Author : W.E. Schiesser
Publisher : CRC Press
Release : 2019-12-17
Category : Medical
ISBN : 9781000763737

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Book Time Delay ODE/PDE Models Description/Summary:

Time delayed (lagged) variables are an inherent feature of biological/physiological systems. For example, infection from a disease may at first be asymptomatic, and only after a delay is the infection apparent so that treatment can begin. Thus, to adequately describe physiological systems, time delays are frequently required and must be included in the equations of mathematical models. The intent of this book is to present a methodology for the formulation and computer implementation of mathematical models based on time delay ordinary differential equations (DODEs) and partial differential equations (DPDEs). The DODE/DPDE methodology is presented through a series of example applications, particularly in biomedical science and engineering (BMSE). The computer-based implementation of the example models is explained with routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, for example, no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The DPDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The example applications can first be executed to confirm the reported solutions, then extended by variation of the parameters and the equation terms, and even the formulation and use of alternative DODE/DPDE models.

Fields, Forces, and Flows in Biological Systems

Author : Alan J Grodzinsky
Publisher : Garland Science
Release : 2011-03-08
Category : Medical
ISBN : 9781136665561

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Book Fields, Forces, and Flows in Biological Systems Description/Summary:

Fields, Forces, and Flows in Biological Systems describes the fundamental driving forces for mass transport, electric current, and fluid flow as they apply to the biology and biophysics of molecules, cells, tissues, and organs. Basic mathematical and engineering tools are presented in the context of biology and physiology.The chapters are structure

Computational Modeling in Tissue Engineering

Author : Liesbet Geris
Publisher : Springer Science & Business Media
Release : 2012-10-30
Category : Technology & Engineering
ISBN : 9783642325632

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Book Computational Modeling in Tissue Engineering Description/Summary:

One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.

Computational Fluid Dynamics and COMSOL Multiphysics

Author : Ashish S. Chaurasia
Publisher : CRC Press
Release : 2021-12-29
Category : Science
ISBN : 9781000400670

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Book Computational Fluid Dynamics and COMSOL Multiphysics Description/Summary:

This textbook covers computational fluid dynamics simulation using COMSOL Multiphysics® Modeling Software in chemical engineering applications. In the volume, the COMSOL Multiphysics package is introduced and applied to solve typical problems in chemical reactors, transport processes, fluid flow, and heat and mass transfer. Inspired by the difficulties of introducing the use of COMSOL Multiphysics software during classroom time, the book incorporates the author’s experience of working with undergraduate, graduate, and postgraduate students to make the book user friendly and that, at the same time, addresses typical examples within the subjects covered in the chemical engineering curriculum. Real-world problems require the use of simulation and optimization tools, and this volume shows how COMSOL Multiphysics software can be used for that purpose. Key features: • Includes over 500 step-by-step screenshots • Shows the graphical user interface of COMSOL, which does not require any programming effort • Provides chapter-end problems for extensive practice along with solutions • Includes actual examples of chemical reactors, transport processes, fluid flow, and heat and mass transfer This book is intended for students who want or need more help to solve chemical engineering assignments using computer software. It can also be used for computational courses in chemical engineering. It will also be a valuable resource for professors, research scientists, and practicing engineers.